Journal of Liver Cancer

Chul Seung Kay

2 Articles

Clinical Experience of Tomotherapy in Oligometastasis and Metastatic Hepatocellular Carcinoma: Chul Seung Kay, Jee Yoon Kim, Jeong Won Jang; Journal of the Korean Liver Cancer Study Group. 2008;8(1):12-15. Published online June 30, 2008

Abstract PDF: Extracranialoligometastasis is most common in lung, liver and bone. The standard treatment is systemic chemotherapy but the value of chemotherapy is limited. So, we can suppose the beneficial effects from the addition of local therapy such as metastasectomy, cooling or heating method of tumor and radiotherapy. Stereotactic body radiotherapy is an alternative approach for surgically unresectable lesions because of proximity to blood vessels or other critical structures and multilobar involvement and for the medically inoperable patients or patients who do not require surgery. Extrahepatic metastasis from hepatocellular carcinoma has no general agreement on the optimal treatment strategy. Helical tomotherapy, a new type of dynamic radiotherapy, is an intensity modulated radiotherapy system equipped with megavoltage computed tomography image guidance. We can precisely deliver high dose of radiation to the tumor with maximal sparing of around normal tissue and simultaneously irradiate the multiple tumor using tomotherapy. We introduce the clinical experience of tomotherapy in oligometastasis and metastatic hepatocellular carcinoma for the last several years.

A Case of Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis Achieving Complete Response with New Therapeutic Modalities: Hyun Young Woo, Jin Dong Kim, Jung Hyun Kwon, Chan Ran You, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Se Hyun Cho, Seung Kew Yoon, Dong Hoon Lee, Ho Jong Chun, Byung Gil Choi, Chul Seung Kay; Journal of the Korean Liver Cancer Study Group. 2008;8(1):124-127. Published online June 30, 2008

Abstract PDF: A 45-year-old man was admitted for the treatment of hepatocellular carcinoma (HCC). He was diagnosed hepatitis B carrier 16 years ago and has not done a routine check. Abdominal CT showed a diffuse infiltrative HCC involving right hepatic lobe with portal vein tumor thrombosis (PVTT) involving right portal vein and proximal portion of left portal vein umbilical portion. With concurrent transcatheter arterial chemotherapy (TAC), helical tomotherapy for portal vein thrombosis was done. With these treatments, main tumor and PVTT was decreased in size markedly and no stain in hepatic angiogram. Due to repeated TAC, hepatic arterial stenosis occurred and TAC was stopped. 3 months after, recurrent tumor was detected in MRI. Radiofrequency ablation followed by High Intensity Focused Ultrasound (HIFU) was done for this recurrent mass. No viable mass was shown in the follow up MRI done 6 months after HIFU.